What Should We Do or Say When Laying Hands on a Sick Person?

There is no technical requirement in Scripture to do anything other than lay your hands on the person.  As long as the person knows why you are doing it and is in agreement with it, you should expect the person to recover because you laid hands on him in the name of Jesus.

I usually speak to the sickness directly and command it to leave in the name of Jesus, but even that is not required.  You can speak to sicknesses without laying hands on people, after all.  We have seen medically “incurable” cancer cases healed by simply speaking without any physical contact.

There are many different ways to minister healing, and laying on of hands is just one of them.   You could also teach the person the Word about healing and have him believe that he receives his healing as he prays, as Jesus taught.  That works too!